Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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256
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270
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256
R&D Systems™ LW 6
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Malate dehydrogenase-2 (MDH2) inhibitor; also inhibits HIF-1α
| Target | Dehydrogenase Inhibitors |
|---|---|
| CAS | 934593-90-5 |
| Purity | 0.98 |
| Chemical Name or Material | Methyl 4-hydroxy-3-[[2-(4-tricyclo[3.3.1.13,7 ]dec-1-ylphenoxy)acetyl]amino]benzoate |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C26H29NO5 |
257
R&D Systems™ ST 045849
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. O-GlcNAc transferase (OGT) inhibitor
| CAS | 442665-87-4 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 2-[(4-Chlorophenyl)imino]tetrahydro-4-oxo-3-(2-tricyclo[3.3.1.13,7]dec-1-ylethyl)-2H-1,3-thiazine-6-carboxylic acid |
| Molecular Formula | C23H27ClN2O3S |
258
R&D Systems™ JHU 37152
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. High affinity and highly potent hM3Dq and hM4Di DREADD agonist; blood brain barrier penetrant
| Target | DREADD Activators |
|---|---|
| CAS | 2369979-67-7 |
| Purity | 0.98 |
| Chemical Name or Material | 8-Chloro-11-(4-ethylpiperazin-1-yl)-1-fluoro-5 H-dibenzo[b,e][1,4 ]diazepine |
| Recommended Storage | Store at RT |
| Molecular Formula | C19H20ClFN4 |
259
R&D Systems™ CBR-470-1
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. PGK1 inhibitior; activates Nrf2
| Target | Nrf2 Activators |
|---|---|
| CAS | 2416095-06-0 |
| Purity | 98% |
| Chemical Name or Material | (3 R,4 S)-rel-4-[(4-Chlorophenyl)sulfonyl]tetrahydro-N-(2-methylpropyl)-3-thiophenamine-1,1-dioxide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C14H20ClNO4S2 |
260
R&D Systems™ BDY FL VH032
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. High-affinity VHL fluorescent probe for TR-FRET and FP assays
261
R&D Systems™ Gilteritinib
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent FLT3 inhibitor; also potently inhibits AXL
| Target | Flt-3/Flk-2/CD135 |
|---|---|
| CAS | 1254053-43-4 |
| Purity | 0.98 |
| Chemical Name or Material | 6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C29H44N8O3 |
262
R&D Systems™ PEAQX tetrasodium salt
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent and GluN2A-selective NMDA antagonist
263
R&D Systems™ Chem-CLIP control probe
A Tocris product, part of R&D Systems. Control probe for Chem-CLIP experiments
264
R&D Systems™ OB-1
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Stomatin-like protein-3 (STOML3) oligomerization inhibitor
| CAS | 300803-69-4 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | Ethyl 5-(1-methyl-4-nitro-1H-imidazol-5-yloxy)-2-phenylbenzofuran-3-carboxylate |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H17N3O6 |
265
R&D Systems™ Squarunkin A Hydrochloride
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. UNC119 chaperone-cargo interaction inhibitor; disrupts Src activation
| Purity | 98% |
|---|---|
| Chemical Name or Material | Ethyl 4-((3,4-dioxo-2-((2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)amino)cyclobut-1-en-1-yl)amino)piperidine-1-carboxylate hydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H32F3N5O4.HCl |
| Formula Weight | 560.01 |
266
R&D Systems™ JNJ 1013NC
A Tocris product, part of R&D Systems. Negative control for the IRAK1 degrader JNJ 1013 (Cat. No. 8029)
267
R&D Systems™ Janelia Fluor 525, Maleimide
A Tocris product, part of R&D Systems. Yellow dye (Reactive group: maleimide). Application: flow cytometry, confocal microscopy, super resolution microscopy including dSTORM & STED. Suitable for live cell imaging
268
R&D Systems™ FM19G11
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. HIF α-subunit inhibitor
| CAS | 329932-55-0 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 2-Oxo-2-(p-tolyl)ethyl 3-(2,4-dinitrobenzamido)benzoate |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C23H17N3O8 |
| Formula Weight | 463.4 |
269
R&D Systems™ PSEM 308 hydrochloride
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist
| Target | Pharmacologically Selective Effector Molecules/PSEM |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 5-Methyl-5,8,9,10,11 A,12-hexahydro-4 H-8,11-ethanopyrido[3 ',2 ':3,4 ]diazepino[6,7,1-hi]indole hydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C17H21N3.HCl |
| Formula Weight | 303.83 |
270
